AGENDA

08:00 – 09:00

Registration and poster set-up 

09:00 – 09:05

Opening remarks

09:05 – 9:50

Keynote Address: Cracks, leaks and waste in the cancer biomarker pipeline

Patrick Bossuyt, Amsterdam University Medical Centers

9:50 – 10:30

Inequalities in cancer detection and diagnosis

There are significant disparities in rates of early detection and diagnosis of cancers between numerous parts of society, including between groups separated by ethnicity, gender, socioeconomic status and geography. This session will explore the reasons for and mechanisms of these differences and their impact on timeliness of detection, and interventions to ameliorate these inequities.

Chairs: Kate Brain, Cardiff University
Carmen Guerra, University of Pennsylvania

Speakers: Jamil Rivers, The Chrysalis Initiative
Steven Patierno, Duke Cancer Institute
Katie Robb, University of Glasgow
Manali Patel, Stanford University School of Medicine and VA Palo Alto Health Care System

10:30 – 11:00

Networking break and poster session

11:00 – 12:10

Inequalities in cancer detection and diagnosis (cont)

Chairs: Kate Brain, Cardiff University
Carmen Guerra, University of Pennsylvania

Speakers: Jamil Rivers, The Chrysalis Initiative
Steven Patierno, Duke Cancer Institute
Katie Robb, University of Glasgow
Manali Patel, Stanford University School of Medicine and VA Palo Alto Health Care System

12:10 – 12:40

Lightning talks

Establishing Rapid Cancer Diagnostic Services (RCDS) in Scotland
Nathan Thompson, University of Strathclyde

How do organizational and socioeconomic factors affect the adherence to colonoscopy surveillance adherence in the Danish FIT-based colorectal cancer screening program.
Sisse Njor, Vejle Hospital, University Hospital of Southern Denmark

How to improve uptake of breast cancer screening and access to breast cancer services for South Asian and African and African – Caribbean women in Leicester.
Haleema Aslam, De Montfort University

A panel of seven protein tumour markers for effective and affordable multi-cancer early detection by artificial intelligence
Mao Mao, SeekIn Inc

12:40 – 13:40

Networking lunch and poster session

13:40 – 14:15

The Great Debate: We need to shift early detection of cancer out of the medical system and deliver it in the community

This debate will focus on the proposition that early detection of cancer should be moved away from medical practices and hospitals and into the community. This lively discussion session will explore the potential benefits and challenges associated with hospital and community-led cancer detection.

Chair: David Crosby, Cancer Research UK

Debaters: Clare Turnbull, Institute of Cancer Research
Peggy Hannon, University of Washington

14:15 – 15:10

Understanding pre-cancers to enable early detection  

The session aims to discuss the detection, characterisation, and biological understanding of progression of pre-cancers to inform early detection. The session will explore how we can go about detecting pre-cancerous lesions or changes (in both solid and haematological conditions) to intercept and prevent progression to malignancy.

Chairs: Sam Janes, University College London
Irene Ghobrial, Dana-Farber Cancer Institute

Speakers: Trevor Graham, Institute of Cancer Research
Margarete Fabre, AstraZeneca
Adam Pennycuick, University College London
Laura DeLong Wood, Johns Hopkins University School of Medicine

15:10 – 15:40

Networking break and poster session

15:40 – 16:50

Understanding pre-cancers to enable early detection  (cont)

Chairs: Sam Janes, University College London
Irene Ghobrial, Dana-Farber Cancer Institute

Speakers: Trevor Graham, Institute of Cancer Research
Margarete Fabre, AstraZeneca
Adam Pennycuick, University College London
Laura DeLong Wood, Johns Hopkins University School of Medicine

16:50 – 17:20

Lightning Talks

Towards A Physiologically Relevant Lung In Vitro Model for Early Cancer Biomarkers
Emmanouela Mitta, University of Manchester

Proteomic Expression Using Exosomes in Intraductal Papillary Mucinous Neoplasms (IPMN) Patients to Inform Risk Stratification
Harmeet Dhani, Biological Dynamics

Identifying biomarkers of progression in genetically engineered mouse models of early ovarian cancer
Matthew Ford, University of Cambridge

17:20 – 17:25

Closing remarks

17:25 – 18:25

Networking drinks and poster session

07:45 – 08:45

Registration and poster set-up 

08:45 – 08:50

Opening remarks

08:50 – 09:25

The Great Debate: All cancer screening must be reserved for ‘high risk’ population

This scientific debate centers around the proposition that all cancer screening should be exclusively reserved for high-risk populations. The debaters will discuss the benefits and challenges of focusing cancer screening efforts solely on individuals at high risk of developing cancer.

Chair: David Crosby, Cancer Research UK

Debaters: Fiona Gilbert, University of Cambridge
Hilary Robbins, International Agency for Research on Cancer

09:25 – 09:55

A conversation with Antonis Antoniou and Sapna Syngal – ‘Can data revolutionise our approach to early detection?’

Speakers: Antonis Antoniou, University of Cambridge
Sapna Syngal, Dana-Farber Cancer Institute

09:55 – 10:25

Lightning talks

Multi-modal Signatures for Enhanced Lung Cancer Detection and Interpretability
Paul Barber, King’s College London

10:25 – 10:55

Networking break and poster session

10:55 – 12:50

Risk stratification to inform early detection

This session will cover the latest developments in identifying, understanding and utilizing at-risk populations in order to inform the development and support the implementation of early detection strategies.

Chairs: Yoryos Lyratzopoulos, University College London (UCL)
Sapna Syngal, Dana-Farber Cancer Institute

Speakers: Rosalind Eeles, The Institute of Cancer Research
Angela Wood, Health Data Research UK / University of Cambridge
Brian Nicholson, University of Oxford
Michael Rosenthal, Harvard University
Helen White, patient advocate

12:50 – 14:00

Networking lunch and poster session

14:00 – 14:45

Panel: Why haven’t the technological and regulatory advances from our learnings of the pandemic accelerated research in the cancer early detection research field?

This panel discussion will examine why the technological and regulatory advances that enabled accelerated development of innovations, fast-tracked implementation and greater data accessibility during the COVID-19 pandemic haven’t improved the landscape for cancer early detection research and the development of cancer diagnostics as was thought possible or even likely a year or more ago.

Chair: Jon Emery, University of Melbourne

Panelists: Chris Whitty, UK Government
Alexander David Borowsky, University of California, Davis
Lisa Lacasse, American Cancer Society 

14:45 – 15:20

Keynote Address: Integration of Imaging and Biomarkers for the Early Detection of Cancer

Edward Patz, Duke University School of Medicine and Grid Therapeutics

15:20 – 15:55

Panel: How can we integrate information coming from traditional imaging with molecular biomarkers and clinical information to aid the early detection of cancer?

This scientific panel discussion will explore strategies for effectively integrating information from traditional imaging techniques, molecular biomarkers, and clinical data to enhance early cancer detection.

Chair: Cristian Tomasetti, City of Hope

Speakers: Edward Patz, Duke University School of Medicine and Grid Therapeutics
Caroline Dive, CRUK Manchester Institute
Shonit Punwani, University College London (UCL)

15:55 – 16:25

Networking break and poster session

16:25 – 17:25

Networking session

In this networking session, participants will engage in small group discussions on a variety of topics. The session aims to foster meaningful conversations, exchange knowledge, and promote collaborations among experts and stakeholders in the field of cancer early detection.

17:25 – 17:30

Closing remarks

17:30 – 18:30

Networking drinks and poster session

19:00 – late

Conference Dinner and Don Listwin Award

08:30 – 09:00

Registration

09:00 – 09:05

Opening remarks

09:05 – 10:00

Multicancer early detection – beyond ctDNA

This session will cover the wide array of multicancer early detection tests in development beyond the tests based on cell-free tumour DNA in the blood.

Chairs: Matthew Thompson, Google LLC
Claude Chelala, Queen Mary University of London

Speakers: Søren Brunak, University of Copenhagen
Paul Brennan, The University of Edinburgh
Garth Funston, Wolfson Institute of Population Health, Queen Mary University of London
Francesco Gatto, Elypta

10:00 – 10:30

Networking break and poster session

10:30 – 11:40

Multicancer early detection – beyond ctDNA (cont)

Chairs: Matthew Thompson, Google LLC
Claude Chelala, Queen Mary University of London

Speakers: Søren Brunak, University of Copenhagen
Paul Brennan, The University of Edinburgh
Garth Funston, Wolfson Institute of Population Health, Queen Mary University of London
Francesco Gatto, Elypta

11:40 – 12:10

Lightning talks

12:10 – 12:45

Panel: Introducing Patient and Public Involvement in your Early Detection Research – Starting the conversation

Involving patients and the public in the design of your early detection research is important and valuable – but knowing how you can go about it can be daunting.  During this interactive panel session, come and talk to our patient and public advocates about integrating patient and public involvement in the work that you’re doing, and hear how they can support you and be actively involved in the decisions made about the research.

We are excited to offer this opportunity to talk with experienced patient and public advocates from the UK and US who are passionate and committed to early detection research. The session will be a chance to ask your questions, pick up some free advice and top tips, and think about how you can best include valuable patient and public involvement in your research!

Chair: Fiona Walter, Queen Mary University of London
Jamil Rivers, The Chrysalis Initiative

Speakers: 
Richard Stephens, Patient advocate
Angela King, Patient advocate

12:45 -13:45

Networking lunch and poster session

13:45 – 14:20

Panel: The Health Economics of Early Detection

In this panel discussion, experts will delve into the practicality and cost-effectiveness of early detection strategies. The discussion aims to shed light on the construction of health economic models for early detection and what the requirements are for an early detection test in order for it to be economically viable. 

Chair: Larry Kessler, University of Washington

Speakers: Natalia Kunst, University of York
Stuart Wright, University of Manchester
Bethany Shinkins, University of Warwick

14:20 – 15:05

Keynote Address: Stem Cell Pathways, Aging and Pre-Cancer Evolution

Catriona Jamieson, Stanford Stem Cell Institute

15:05 – 15:20

Conference closing remarks and poster prize winners