AGENDA

3pm – 7pm

 Registration check-in table open

5pm – 8pm

Trainee Networking event

7:30am – 5:30pm

Registration check-in table open

7:30am – 8:30am

Breakfast

8:30am – 8:35am

Day 1, Opening remarks – Shelley Barton

8:35am – 9:15am

Keynote: Population and tumor heterogeneity in cancer genome science
Speaker: John Carpten
* 10 minutes for Q&A

9:15am – 11:40am

Session 1: From models to mechanisms to humans
Topic chairs: Simon Leedham & Victor Velculescu
Speakers: Jos Jonkers, Ryan Schenck, Sabine Tejpar, Victor Velculescu
* 20 minute session break from 10:10am-10:30am

11:40am – 11:45am

Lightning talk 1 – Yeuk Pin Gladys Poon – The clonal evolution preceding leukemia development revealed using single-cell DNA sequencing

11:45am – 11:50am

Lightning talk 2 – Shiqin Liu – Shed Trop2 Extracellular Domain is a Potential Liquid Biomarker for High-risk Prostate Cancer and a Regulator of Prostate Cancer Progression

11:50am – 12:50pm

Lunch

1:00pm – 1:45pm

Panel: How should we evaluate Multi Cancer Early Detection Tests?
Moderator: Michelle Le Beau
Speakers: Allan Hackshaw, Minetta Liu, Anne Mackie, Josh Ofman
* 25 minutes for Q&A

1:45pm – 4:10pm

Session 2: Emerging technologies for early detection and precision diagnosis
Topic chairs: Rob West & Thuy Ngo
Speakers: Brian Cunningham, Thuy Ngo, Mirabela Rusu, Rob West
* 20 minute session break from 2:40pm-3pm

4:10pm – 4:15pm

Lightning talk 3 – Jie Wang – Acoustic Fabrication of Living Cardiomyocyte-based Hybrid Biorobots

4:15pm – 4:20pm

Lightning talk 4 – Travis Moore – Robust CNV detection using single-cell ATAC-seq

4:20pm – 4:55pm

Great Debate 1: There is no such thing as over-diagnosis. Every diagnosis will help us better understand the biology of the cancer, eventually advancing early cancer detection and management.
Speakers: Nora Pashayan & Eithne Costello

5pm – 6:30pm

Networking and Drinks Poster Reception

7:30am – 4:30pm

Registration check-in table open

8am – 9am

Breakfast

9am – 9:05am

Day 2, Opening remarks – Tanya Stoyanova

9:05am – 10:05am

Keynote Panel: A funding agency perspective on early detection
Speakers: Karen Knudsen, Phil Castle, Catherine Elliott
* 25 minutes for Q&A

10:05am – 12:30pm

Session 3: Microbiological risk factors for early detection
Topic chairs: Xin Lu & Zhenzhen Zhang
Speakers: Emma Allen-Vercoe, Curtis Huttenhower, Gabe Kwong and Zhenzhen Zhang
* 20 minute session break from 11am-11:20am

12:30pm – 12:35pm

Lightning talk 5 – Danielle Brasino – A New, Organ-on-Chip Platform to Study the Relationship Between Gut Microbiota and Distal Tumors

12:35pm – 12:40pm

Lightning talk 6 – Michael Fadel – Diagnostic performance of a non-invasive breath test for colorectal cancer: COlorectal BReath Analysis 1 (COBRA1) study

12:40pm – 1:40pm

Lunch

1:50pm – 2:35pm

Panel: What can we learn from trials that return unexpected results on mortality benefit from early detection biomarkers/tests?
Moderator: Peter Johnson
Speakers: Christine Berg, Usha Menon
* 25 minutes for Q&A

2:35pm – 3:10pm

Great Debate 2: Single-organ cancer screening is failing public health – Multi-cancer early detection tests are the only way forward
Speakers: Paul Limburg & Bob Steele

3:10pm – 4:40pm

Networking and Drinks Poster Reception

4:40pm – 5pm

Break

5pm – 5:30pm

Shuttles to The Redd

5:30pm – 5:50pm

Don Listwin Award Presentation at The Redd

5:50pm – 7:20pm

Conference Dinner at The Redd

7:20pm

Shuttles back to The Nines

7:30am – 12pm

Registration check-in table open

8am – 9am

Breakfast

9am – 9:05am

Day 3, Opening remarks – George Hanna

9:05am – 9:10am

Lightning talk 7 – Joshua Bull – Mathematical Tools for Spatial Analysis of Multiplex Medical Images

9:10am – 9:15am

Lightning talk 8 – Elinor Nemlander – Predicting lung cancer in never smokers, former smokers and current smokers using machine learning – results from a computer-based detailed symptom questionnaire given to patients investigated at a specialist lung clinic

9:15am – 11:40am

Session 4: What is needed for an earlier cancer detection test to have clinical impact?
Topic chairs: Tom Beer & Rebecca Fitzgerald
Speakers: Hormuzd Katki, Larry Kessler, Chris Peters, Sharmila Anandasabapathy
* 20 minute session break from 10:10am-10:30am

11:40am – 11:50am

Conference closing remarks – George Hanna